What this is
A small, focused reference for people who just got a GLP‑1 prescription — or are thinking about one — and have ordinary, important questions that shouldn't require a doctor's visit or a Reddit deep dive.
When someone starts Wegovy or Mounjaro, three questions tend to surface in the first week: How much weight will I actually lose? How much is this going to cost? When do I increase my dose? Each of those has a real answer grounded in the published clinical-trial data — and that data is what GLP Index is built on.
What it isn't
GLP Index is not a medical provider. We don't diagnose, treat, or prescribe. We don't run a telehealth practice. We don't connect you to one. We have no affiliate relationships of any kind on the calculator pages — and if we ever do, they will be labelled and excluded from the medical math.
The projections you'll see are averages from clinical trials. Your individual response will vary — possibly significantly. Nothing on this site is medical advice. Always talk to your healthcare provider before starting, stopping, or changing any medication.
Data sources
Every projected number on this site traces back to a peer-reviewed clinical trial. We don't model. We don't blend. We don't extrapolate beyond the trial endpoints.
- Wegovy HDsemaglutide 7.2 mg STEP UP · Novo Nordisk et al.
N Engl J Med 392:1501 (2025) ↗ - Wegovysemaglutide 2.4 mg STEP 1 · Wilding et al.
N Engl J Med 384:989 (2021) ↗ - Ozempicsemaglutide 1 mg STEP 2 · Davies et al.
Lancet 397:971 (2021) ↗ - Mounjarotirzepatide SURPASS-2, SURMOUNT-1
NEJM 385:503 / 387:205 ↗ - Zepboundtirzepatide SURMOUNT-1 · Jastreboff et al.
N Engl J Med 387:205 (2022) ↗
Dose escalation schedules come from FDA-approved prescribing information for each medication. Drug pricing is updated manually monthly and reflects estimates from GoodRx and named telehealth providers — actual prices vary by pharmacy, location, and insurance.
How we project
The weight-loss timeline takes the published mean percentage loss at each trial week and applies it to your starting weight. We don't apply a personalization model — there isn't one we'd trust. The chart shows the trial average and notes the variance from the published data so you can see where your individual outcome might land.
The dose schedule is a deterministic walk through the FDA label, anchored to a start date you choose. The cost comparison reflects current cash, GoodRx, manufacturer-savings-card, and telehealth pricing pulled in the month listed at the top of the comparison page.
How we're funded
GLP Index is free and independently maintained. No advertising. No affiliate links on any calculator page. No paid placements.
In the future, we may add affiliate partnerships with licensed telehealth providers — clearly labelled, and never inside the calculator outputs. If we do, we'll only partner with providers that prescribe FDA-approved, brand-name GLP-1 medications through licensed physicians. We will not partner with compounding pharmacies selling unapproved formulations.
Last updated
Trial data: stable since the original publications (we link to peer-reviewed sources rather than restating numbers). FDA prescribing information: checked quarterly. Pricing: refreshed monthly. The data version is shown at the top of every page.
Current build · v.2026.05 · pricing pulled May 1, 2026
Medical disclaimer
The information on GLP Index is for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
Weight loss projections are estimates based on averages from published clinical trials conducted under controlled conditions. Individual results vary based on starting weight, adherence, diet, activity, metabolism, and other factors. The trial populations may not represent your individual situation.
Drug pricing is for general comparison and may not reflect the price you'll pay at your specific pharmacy. Prices change frequently and vary by location, insurance, and pharmacy.
If you are experiencing a medical emergency, call 911 or go to your nearest emergency room.